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TITLE: Study and development of a flow control system adapted to the physiological level for a ventricular assist device

author(s): Dornellas, M.P., Bock, E.G.P. & Santos, B.J.

ABSTRACT: Heart failure (HF) is a syndrome that makes the heart unable to pump blood at physiological levels. The most recommended treatment for a patient with advanced HF is heart transplantation, although this is limited by the number of donors. Alternatively, Ventricular Assist Devices (VADs) can be used clinically to mitigate this limitation. The rotary-type VAD is the most widely used today and is a device that requires improvement, since it can develop complications, such as thrombus formation and gastrointestinal bleeding, among other examples. The aim of this work is to develop flow control techniques adapted to the patient's physical demands, by analyzing the functioning of a clinically tested physiological controller for VADs, which is based on detecting the patient's physical activity levels by varying the heart rate to adjust the VAD flow and prevent side effects. The speed control module inspired by the evaluated controller was thoroughly implemented according to the literature studied in a computer environment using the Dev C++ and Google Colab programs. The performance results obtained were studied in detail. Changes in the patient's cardiac status were able to influence the speed control of the VAD pump.

KEYWORDS: Heart failure, Ventricular Assist Device (VAD), Physiological control system.

CITATION: Dornellas et al. Study and development of a flow control system adapted to the physiological level for a ventricular assist device. The Academic Society Journal, 7(4) 122-137, 2023. DOI: doi.org/10.32640/tasj.2023.4.122.

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